A prospective observational study to correlate radiological findings with cytohistology for diagnosis of ovarian tumor

Background: Literature assessing the utility of simple technique like imaging modalities for accurate preoperative diagnosis of ovarian masses is scarce; thus, this study was undertaken to evaluate the diagnostic accuracy of radiological modalities for diagnosis of the nature of the ovarian tumor as compared to cyto/histopathological reports.Methodology: This observational study was conducted on 40 patients presenting with ovarian masses. All the cases were subjected to history taking and thorough examination. Ultrasonography and color Doppler was performed on all the cases and findings were documented with respect to IOTA rules and findings were correlated with histopathology/cytology. Results: B mode features were present in 32.5%, M mode features were in 62.5% women and in 5% women results were inconclusive (Table 1).Histopathology/cytology was considered gold standard for and about 65% of the ovarian masses were malignant whereas 35% were benign. We found that when inconclusive cases were included, sensitivity was 86%, specificity was 80%, positive predictive value was 72.2%, negative predictive value was 90%. After excluding inconclusive cases, we found that sensitivity was 78.5%, specificity was 87%, positive predictive value was 78.5%, negative predictive value was 87%.Conclusions: Although CT/MRI are considered for diagnosing ovarian tumor but the advantages of USG are its easy availability, reasonable cost and lack of radiation exposure. IOTA simple USG rules are highly sensitive and specific in prediction of ovarian malignancy and also easy to use and easily reproducible. Thus, USG examination help in better management of patients in terms of time, cost and better prognosis. This will also avoid the need for costlier modalities like CT, MRI.

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Publication Details

Journal
International Journal of Clinical Obstetrics and Gynaecology
Published
2024-09-01
DOI
https://doi.org/10.33545/gynae.2024.v8.i5a.1503
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
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article

A prospective observational study to correlate radiological findings with cytohistology for diagnosis of ovarian tumor

Meenakshi Chauhan, Rajeev Sen, Monika Dalal, Shilpa Hurmade et al.
International Journal of Clinical Obstetrics and Gynaecology
Ovarian cancer diagnosis and treatment
article

A prospective observational study to correlate radiological findings with cytohistology for diagnosis of ovarian tumor

Meenakshi Chauhan, Rajeev Sen, Monika Dalal, Shilpa Hurmade, Jyotsana Sen
article en

Abstract

Background: Literature assessing the utility of simple technique like imaging modalities for accurate preoperative diagnosis of ovarian masses is scarce; thus, this study was undertaken to evaluate the diagnostic accuracy of radiological modalities for diagnosis of the nature of the ovarian tumor as compared to cyto/histopathological reports.Methodology: This observational study was conducted on 40 patients presenting with ovarian masses. All the cases were subjected to history taking and thorough examination. Ultrasonography and color Doppler was performed on all the cases and findings were documented with respect to IOTA rules and findings were correlated with histopathology/cytology. Results: B mode features were present in 32.5%, M mode features were in 62.5% women and in 5% women results were inconclusive (Table 1).Histopathology/cytology was considered gold standard for and about 65% of the ovarian masses were malignant whereas 35% were benign. We found that when inconclusive cases were included, sensitivity was 86%, specificity was 80%, positive predictive value was 72.2%, negative predictive value was 90%. After excluding inconclusive cases, we found that sensitivity was 78.5%, specificity was 87%, positive predictive value was 78.5%, negative predictive value was 87%.Conclusions: Although CT/MRI are considered for diagnosing ovarian tumor but the advantages of USG are its easy availability, reasonable cost and lack of radiation exposure. IOTA simple USG rules are highly sensitive and specific in prediction of ovarian malignancy and also easy to use and easily reproducible. Thus, USG examination help in better management of patients in terms of time, cost and better prognosis. This will also avoid the need for costlier modalities like CT, MRI.

International Journal of Clinical Obstetrics and GynaecologyVol. 8(5)
Zero hunger
Openalex Percentile: Top 77%
Ovarian cancer diagnosis and treatment
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A prospective observational study to correlate radiological findings with cytohistology for diagnosis of ovarian tumor — Meenakshi Chauhan, Rajeev Sen, et al. · International Journal of Clinical Obstetrics and Gynaecology (2024) | TGRS Research Map | TGRS