Elevated BEAN1 expression correlates with poor prognosis, immune evasion, and chemotherapy resistance in rectal adenocarcinoma
This research offers initial evidence that BEAN1 is linked to unfavorable prognosis, immune escape, and resistance to chemotherapy in READ. BEAN1 appears to be a promising new biomarker and potential therapeutic target, warranting further investigation into its potential clinical applications in improving treatment outcomes for READ patients.
Authors
- Yi Chen (ORCID: https://orcid.org/0000-0001-7960-8374)
- Xiangyue Zeng
- Tuoxian Tang (ORCID: https://orcid.org/0000-0002-6747-461X)
- Zhimin Wu (ORCID: https://orcid.org/0000-0002-7374-6693)
- Yipeng Pan
- Tiannake Shapaer
- Zeliang Zhao
Institutions
- Guiyang Medical University (CN)
- Xinjiang Medical University (CN)
- Sir Run Run Shaw Hospital (CN)
- Tumor Hospital of Xinjiang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
- Zhejiang University (CN)
- University of Pennsylvania (US)
Publication Details
- Journal
- Discover Oncology
- Published
- 2024-09-14
- DOI
- https://doi.org/10.1007/s12672-024-01321-5
- Citations
- 27
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 11.31