Homologous cell membrane-based hydrogel creates spatiotemporal niches to improve outcomes of dysregulated chronic wound healing
The (M2M + TGF-β)@HAMA hydrogel dressing improves the outcomes of dysregulated chronic wound healing by protecting the open wound from repeated bacterial infections, reprogramming endogenous monocytes and M1 macrophages into an M2-phenotype, as well as enhancing fibroblastic proliferation and migration for matrix remodeling and granulation tissue formation.Image 1.
Authors
- Heying Chen
- Yubo Wu
- Yilu Ni (ORCID: https://orcid.org/0000-0002-0402-4734)
- Haiyan He (ORCID: https://orcid.org/0000-0002-3701-7725)
- Qi Jia
- Jufen Ye
- Dafeng Xie
- Yanlin Peng
- Yijuan Ding
- Ziwen Su
Institutions
- Chongqing Medical University (CN)
Publication Details
- Journal
- Materials Today Bio
- Published
- 2024-09-14
- DOI
- https://doi.org/10.1016/j.mtbio.2024.101243
- Citations
- 3
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.75