Management of severe capecitabine-induced corneal toxicity
We report the first case of severe visual impairment due to capecitabine-induced corneal toxicity. Early corneal scraping, especially when confronted with profound vision loss, may yield better outcomes compared to relying on spontaneous recovery after capecitabine discontinuation. Patients experiencing ocular discomfort and vision loss, while receiving capecitabine therapy, should be referred for semi-urgent ophthalmological examination.
Authors
- Hannelore Denys (ORCID: https://orcid.org/0000-0002-8897-9430)
- Jo Van Dorpe (ORCID: https://orcid.org/0000-0001-8175-2930)
- Dimitri Roels (ORCID: https://orcid.org/0000-0003-0051-0855)
- Mathieu Heyvaert
Institutions
- Ghent University Hospital (BE)
- Ghent University (BE)
- Cancer Research Institute Ghent (BE)
Publication Details
- Journal
- American Journal of Ophthalmology Case Reports
- Published
- 2024-09-14
- DOI
- https://doi.org/10.1016/j.ajoc.2024.102174
- Citations
- 1
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- Universitair Ziekenhuis Gent
- Universiteit Gent