Genomic Characteristics of a Carbapenem-Resistant Klebsiella pneumoniae Co-Carrying blaNDM-5 and blaKPC-2 Capsular Type KL25 Recovered from a County Level Hospital in China
This study reported the genomic characteristics of a multidrug-resistant ST11 <i>K. pneumoniae</i> with capsular serotype KL25, co-carrying <i>bla</i> <sub>NDM-5</sub>, two copies of <i>bla</i> <sub>KPC-2</sub> genes and multiple plasmid-borne virulence genes in China. These findings will provide important knowledge of the antibiotic resistance mechanisms, genomic epidemiological characteristics and transmission dynamics of multidrug-resistant <i>K. pneumoniae</i>.
Authors
- Yuanzhong Fang
- Lidong Xu
- Minfei Peng (ORCID: https://orcid.org/0000-0002-5446-2986)
- Danni Bao (ORCID: https://orcid.org/0000-0002-3186-1968)
- Qiuying Zhang (ORCID: https://orcid.org/0000-0003-4667-6017)
- Kainan Jin
- Juan Jin
- Linyuan Gu
Institutions
- Wenzhou Medical University (CN)
- Suizhou Central Hospital (CN)
- Hangzhou Women’s Hospital (CN)
- Taizhou First People's Hospital (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- Zhejiang Taizhou Hospital (CN)
- Hangzhou Children's Hospital (CN)
- Taizhou University (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2147/idr.s479560
- Citations
- 2
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.34
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province