Dosing and Misuse of Buprenorphine in the New Jersey Department of Corrections.

Opioid use disorder is common in incarcerated persons, and concern about the diversion of buprenorphine is a barrier to treatment. We conducted a retrospective chart review of incarcerated persons in the New Jersey Department of Corrections who received charges for misuse of medication, including buprenorphine, hypothesizing that the prescription of buprenorphine monoproduct, multiple tabs or films of buprenorphine, or higher doses of buprenorphine would be associated with more diversion incidents. Within the dosing range of 2 to 12 mg, there were more incidents of diversion of buprenorphine monoproduct (24.3%) compared with buprenorphine-naloxone (10.7%, <i>p</i> = .004). More incidents of diversion were seen when multiple films or tabs of buprenorphine product were prescribed (21.7%, comparison 12.7%, <i>p</i> = .01). This observation held when considering multiple buprenorphine-naloxone films, but not multiple buprenorphine tablets. No statistically significant association was found for institutional diversion charges related to higher doses of buprenorphine products. These results suggest that, within the dosing range of buprenorphine used in the New Jersey Department of Corrections, misuse charges were not associated with higher doses although were associated with prescribing buprenorphine monoproduct and multiple films of buprenorphine-naloxone.

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Publication Details

Journal
PubMed
Published
2024-12-12
DOI
https://doi.org/10.29158/jaapl.240071-24
Citations
2
Primary Topic
Opioid Use Disorder Treatment
Type
article
Field-Weighted Citation Impact
1.09
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article

Dosing and Misuse of Buprenorphine in the New Jersey Department of Corrections.

T. Martin, Anthony Tamburello
2 citations
PubMed
Opioid Use Disorder Treatment
1.09
article

Dosing and Misuse of Buprenorphine in the New Jersey Department of Corrections.

T. Martin, Anthony Tamburello
article en
2 citations

Abstract

Opioid use disorder is common in incarcerated persons, and concern about the diversion of buprenorphine is a barrier to treatment. We conducted a retrospective chart review of incarcerated persons in the New Jersey Department of Corrections who received charges for misuse of medication, including buprenorphine, hypothesizing that the prescription of buprenorphine monoproduct, multiple tabs or films of buprenorphine, or higher doses of buprenorphine would be associated with more diversion incidents. Within the dosing range of 2 to 12 mg, there were more incidents of diversion of buprenorphine monoproduct (24.3%) compared with buprenorphine-naloxone (10.7%, <i>p</i> = .004). More incidents of diversion were seen when multiple films or tabs of buprenorphine product were prescribed (21.7%, comparison 12.7%, <i>p</i> = .01). This observation held when considering multiple buprenorphine-naloxone films, but not multiple buprenorphine tablets. No statistically significant association was found for institutional diversion charges related to higher doses of buprenorphine products. These results suggest that, within the dosing range of buprenorphine used in the New Jersey Department of Corrections, misuse charges were not associated with higher doses although were associated with prescribing buprenorphine monoproduct and multiple films of buprenorphine-naloxone.

PubMedVol. 52(4)
Environmental and Occupational Health Sciences Institute (US)
Openalex Percentile: Top 21%
Opioid Use Disorder Treatment
1.09
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Dosing and Misuse of Buprenorphine in the New Jersey Department of Corrections. — T. Martin, Anthony Tamburello · PubMed (2024) | TGRS Research Map | TGRS