Mechanical Thrombectomy Versus Intravenous Thrombolysis in Distal Medium Vessel Acute Ischemic Stroke: A Multinational Multicenter Propensity Score-Matched Study
The results of this study indicate that while MT-IVT and IVT alone show similar functional and mortality outcomes in DMVO patients, MT-IVT presents a higher risk of hemorrhagic complications, thus MT-IVT may not routinely offer additional benefits over IVT alone for all DMVO stroke patients. Further prospective randomized trials are needed to identify patient subgroups most likely to benefit from MT-IVT treatment in DMVO.
Authors
- Jeremy Josef Heit (ORCID: https://orcid.org/0000-0003-1055-8000)
- Mohammad Ali Aziz‐Sultan (ORCID: https://orcid.org/0009-0000-0980-7511)
- Joshua D. Bernstock (ORCID: https://orcid.org/0000-0002-7814-3867)
- Tobias Djamsched Faizy (ORCID: https://orcid.org/0000-0002-1631-2020)
- Ajit S Puri (ORCID: https://orcid.org/0000-0002-6978-6457)
- Hamza A. Shaikh (ORCID: https://orcid.org/0000-0001-8163-4600)
- Luca Scarcia (ORCID: https://orcid.org/0000-0002-1316-0383)
- Constantin Hecker (ORCID: https://orcid.org/0000-0003-0521-8570)
- Pablo Harker (ORCID: https://orcid.org/0000-0003-0263-8748)
- Alessandro Pedicelli (ORCID: https://orcid.org/0000-0002-2558-8838)
- Benjamin Pulli (ORCID: https://orcid.org/0000-0002-1795-9897)
- Benjamin Gory (ORCID: https://orcid.org/0000-0001-8424-4464)
- Ricardo Varela (ORCID: https://orcid.org/0000-0002-8072-1013)
- David S. Liebeskind (ORCID: https://orcid.org/0000-0002-5109-8736)
- Aymeric Rouchaud (ORCID: https://orcid.org/0000-0003-0902-3375)
- Hamza Adel Salim (ORCID: https://orcid.org/0000-0002-5208-8425)
- Vincent Costalat (ORCID: https://orcid.org/0000-0001-8428-9101)
- Benjamin Yong‐Qiang Tan (ORCID: https://orcid.org/0000-0003-1824-9077)
- Nimer Adeeb (ORCID: https://orcid.org/0000-0002-8668-7629)
- Julian Spears (ORCID: https://orcid.org/0000-0002-4111-6929)
- David Altschul (ORCID: https://orcid.org/0000-0002-5130-1378)
- Kareem El Naamani (ORCID: https://orcid.org/0000-0001-5294-1003)
- Sunil G. Sheth (ORCID: https://orcid.org/0000-0003-0399-4402)
- Muhammed Amir Essibayi (ORCID: https://orcid.org/0000-0001-8325-2382)
- Boris Lubicz (ORCID: https://orcid.org/0000-0001-8312-2115)
- Nestor R. Gonzalez (ORCID: https://orcid.org/0000-0002-8277-6317)
- James Ernest Siegler (ORCID: https://orcid.org/0000-0003-0287-3967)
- Nicole M Cancelliere (ORCID: https://orcid.org/0000-0002-8703-4304)
- Nils Henninger (ORCID: https://orcid.org/0000-0002-3883-5623)
- Adam Andrew Dmytriw (ORCID: https://orcid.org/0000-0003-0131-5699)
- Sherief Ghozy (ORCID: https://orcid.org/0000-0001-5629-3023)
- Leonardo Renieri (ORCID: https://orcid.org/0000-0001-8966-8266)
- Jane Khalife (ORCID: https://orcid.org/0000-0003-3662-3886)
- Marco Colasurdo (ORCID: https://orcid.org/0000-0002-7823-3088)
- Thanh N. Nguyen (ORCID: https://orcid.org/0000-0002-2810-1685)
- Jens Fiehler (ORCID: https://orcid.org/0000-0001-8533-7478)
- Frédéric Clarençon (ORCID: https://orcid.org/0000-0002-6442-8239)
- Thomas R. Marotta (ORCID: https://orcid.org/0000-0002-2480-2054)
- João Pedro Filipe (ORCID: https://orcid.org/0000-0002-7232-9820)
- Ashkan Mowla (ORCID: https://orcid.org/0000-0001-5352-8747)
- Xavier Barreau (ORCID: https://orcid.org/0000-0002-4932-1484)
- Amanda Baker (ORCID: https://orcid.org/0000-0002-0291-707X)
- Takahiro Ota (ORCID: https://orcid.org/0000-0002-5108-6719)
- Andrea Maria Alexandre (ORCID: https://orcid.org/0000-0002-8080-3916)
- Illario Tancredi (ORCID: https://orcid.org/0000-0001-5190-2635)
- Vivek Srikar Yedavalli (ORCID: https://orcid.org/0000-0002-2450-4014)
- Christian Paul Stracke (ORCID: https://orcid.org/0000-0003-1242-4372)
- Răzvan Alexandru Radu (ORCID: https://orcid.org/0000-0001-6375-8466)
- Vítor Mendes Pereira (ORCID: https://orcid.org/0000-0002-6804-3985)
- Sri Hari Sundararajan (ORCID: https://orcid.org/0000-0002-6017-3603)
- Adrien Guenego (ORCID: https://orcid.org/0000-0001-7281-1652)
- Basel Musmar (ORCID: https://orcid.org/0009-0000-4910-6090)
- Aman B. Patel (ORCID: https://orcid.org/0000-0001-9022-411X)
- Christian Dyzmann (ORCID: https://orcid.org/0009-0002-7323-154X)
- Erwah Kalsoum (ORCID: https://orcid.org/0000-0002-8575-0606)
- Arundhati Biswas (ORCID: https://orcid.org/0000-0003-1645-5563)
- Anna Luisa Kühn
- Robert W. Regenhardt (ORCID: https://orcid.org/0000-0003-2958-3484)
- Markus A Möhlenbruch
- Pascal Jabbour (ORCID: https://orcid.org/0000-0002-1544-4910)
Institutions
- University of Southern California (US)
- Louisiana State University (US)
- Cedars-Sinai Medical Center (US)
- Brigham and Women's Hospital (US)
- Boston Medical Center (US)
- St. Michael's Hospital (CA)
- Albert Einstein College of Medicine (US)
- Beth Israel Deaconess Medical Center (US)
- Westchester Medical Center (US)
- Montefiore Medical Center (US)
- Harvard University (US)
- Johns Hopkins University (US)
- Thomas Jefferson University (US)
- Inserm (FR)
- Universität Hamburg (DE)
- University of California, Los Angeles (US)
- Oregon Health & Science University (US)
- National University of Singapore (SG)
- University of Massachusetts Chan Medical School (US)
- New York Medical College (US)
- Université de Montpellier (FR)
- Heidelberg University (DE)
- Paracelsus Medical University (AT)
- Cooper University Hospital (US)
- Erasmus Hospital (BE)
- University Hospital Heidelberg (DE)
- Agostino Gemelli University Polyclinic (IT)
- Johns Hopkins Bayview Medical Center (US)
- Sorbonne Université (FR)
- Massachusetts General Hospital (US)
- Centre Hospitalier Régional et Universitaire de Nancy (FR)
- Sana Kliniken AG (DE)
- University Hospital Münster (DE)
- Bordeaux Population Health (FR)
- University Medical Center Hamburg-Eppendorf (DE)
- Hôpital Gui de Chauliac (FR)
- Imagerie Adaptative Diagnostique et Interventionnelle (FR)
- Pitié-Salpêtrière Hospital (FR)
- St Michael's Hospital (GB)
- Stanford Medicine (US)
- Hôpital Civil de Charleroi (BE)
- National University Hospital (SG)
- Mayo Clinic in Florida (US)
- Tokyo Metropolitan Tama Medical Center (JP)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Centro Hospitalar do Porto (PT)
- Neurological Surgery (US)
- Hôpital Dupuytren (FR)
- University of Cincinnati (US)
- Université de Limoges (FR)
- Université de Lorraine (FR)
- The University of Texas Health Science Center at Houston (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Journal of Stroke
- Published
- 2024-09-13
- DOI
- https://doi.org/10.5853/jos.2024.01389
- Citations
- 30
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 11.60
Funders
- Stryker
- National Institutes of Health