Quercetin 7-rhamnoside from Sorbaria sorbifolia exerts anti-hepatocellular carcinoma effect via DHRS13/apoptotic pathway
Elevated DHRS13 expression contributes to HCC progression. Q7R effectively downregulates DHRS13, encouraging apoptosis and impeding HCC growth. As a result, Q7R shows potential as a therapeutic agent for HCC treatment, targeting the apoptotic pathway through DHRS13 regulation.
Authors
- Ying Dang
- Wenzhi Yao (ORCID: https://orcid.org/0000-0002-4874-0169)
- Hai Hai
- Jing Li (ORCID: https://orcid.org/0000-0002-3977-1641)
- Xu Chen (ORCID: https://orcid.org/0000-0002-7299-3238)
- Jiamei Zhang (ORCID: https://orcid.org/0000-0001-6654-3241)
- Yu Dong (ORCID: https://orcid.org/0000-0002-4836-4933)
- W. Kou
- Zhaohua Xu
- Jianping Shi
Institutions
- Academy of Military Medical Sciences (CN)
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2024-09-13
- DOI
- https://doi.org/10.1016/j.phymed.2024.156031
- Citations
- 7
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.64
Funders
- Natural Science Foundation of Inner Mongolia