Plasma Circulating Metabolites Associated With Steatotic Liver Disease and Liver Enzymes: A Multiplatform Population-Based Study
Our study indicates a landscape of circulating metabolites associated with SLD. The identified metabolites may contribute to a better understanding of the metabolic pathways underlying SLD and hold promising for potential biomarkers in early diagnosis and monitoring of the disease.
Authors
- Laurens A. van Kleef (ORCID: https://orcid.org/0000-0002-2333-1182)
- Jill M. Norris (ORCID: https://orcid.org/0000-0001-8674-2598)
- Ibrahim Ayada (ORCID: https://orcid.org/0000-0002-8197-3458)
- Jessica Williams‐Nguyen (ORCID: https://orcid.org/0000-0003-0643-7433)
- Robert J. de Knegt (ORCID: https://orcid.org/0000-0003-0934-6975)
- M. Arfan Ikram (ORCID: https://orcid.org/0000-0003-0372-8585)
- Yasir J. Abozaid (ORCID: https://orcid.org/0000-0003-3720-5205)
- Nicholas J. Timpson (ORCID: https://orcid.org/0000-0002-7141-9189)
- Mohsen Ghanbari (ORCID: https://orcid.org/0000-0002-9476-7143)
- Neil Goulding (ORCID: https://orcid.org/0000-0002-2488-4598)
- Robert C. Kaplan (ORCID: https://orcid.org/0000-0003-1571-4615)
- Willem Pieter Brouwer (ORCID: https://orcid.org/0000-0001-8713-1481)
- Lynne E. Wagenknecht (ORCID: https://orcid.org/0000-0002-9980-0889)
- Yii-Der Ida Chen
Institutions
- Albert Einstein College of Medicine (US)
- Colorado School of Public Health (US)
- UCLA Medical Center (US)
- University of Washington Medical Center (US)
- Erasmus MC (NL)
- University of Bristol (GB)
- Harbor–UCLA Medical Center (US)
- Wake Forest University (US)
- University of Colorado Anschutz Medical Campus (US)
- Medical Research Council (GB)
Publication Details
- Journal
- Gastro Hep Advances
- Published
- 2024-09-13
- DOI
- https://doi.org/10.1016/j.gastha.2024.09.006
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- Office of Dietary Supplements
- University of Miami
- Northwestern University
- San Diego State University
- European Federation of Pharmaceutical Industries and Associations
- European Commission
- University of Bristol
- ZonMw
- Erasmus Medisch Centrum
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Innovative Medicines Initiative
- Medical Research Council
- National Heart, Lung, and Blood Institute
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Center on Minority Health and Health Disparities
- National Institute on Minority Health and Health Disparities