Unraveling the role of ADAMs in clinical heterogeneity and the immune microenvironment of hepatocellular carcinoma: insights from single-cell, spatial transcriptomics, and bulk RNA sequencing

This study represented the inaugural report on the deleterious impact and prognostic significance of ADAM family signals within the tumor microenvironment of HCC.

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Publication Details

Journal
Frontiers in Immunology
Published
2024-09-13
DOI
https://doi.org/10.3389/fimmu.2024.1461424
Citations
8
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
1.92
Controls
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article

Unraveling the role of ADAMs in clinical heterogeneity and the immune microenvironment of hepatocellular carcinoma: insights from single-cell, spatial transcriptomics, and bulk RNA sequencing

Tianfu Wei, Hewen Guan, Kai Liu, Qihang Yuan et al.
8 citations
Frontiers in Immunology
Immune Cell Function and Interaction
1.92
article

Unraveling the role of ADAMs in clinical heterogeneity and the immune microenvironment of hepatocellular carcinoma: insights from single-cell, spatial transcriptomics, and bulk RNA sequencing

Tianfu Wei, Hewen Guan, Kai Liu, Qihang Yuan, Junhong Chen, Yuying Cui, Chang Fu
article en
8 citations

Abstract

This study represented the inaugural report on the deleterious impact and prognostic significance of ADAM family signals within the tumor microenvironment of HCC.

Frontiers in ImmunologyVol. 15
Dalian Medical University (CN), Jilin University (CN), First Hospital of Jilin University (CN), First Affiliated Hospital of Dalian Medical University (CN)
Good health and well-being
Openalex Percentile: Top 14%
Immune Cell Function and Interaction
1.92
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