Low prevalence of HIV in the northern Cameroon: contribution of some AIDS restriction genes and potential implications for gene therapy
The higher frequency of HIV-protective alleles in the northern regions may be a contributing factor to the lower prevalence of HIV. Nevertheless, this should be reinforced by other preventive and surveillance methods to guarantee the sustained low prevalence. HIV can develop resistance through the process of mutation, but the host targets themselves are genetically stable. The study of these host genetic restriction factors is of great value in the design of a practical cure for HIV infection or an effective vaccine.
Authors
- Aline Tiga (ORCID: https://orcid.org/0000-0002-4134-6150)
- Patrice Djataou
- Moussa Djaouda
- Elise Elong (ORCID: https://orcid.org/0000-0002-3558-6748)
- Alexis Ndjolo (ORCID: https://orcid.org/0000-0002-4951-9271)
- Marie Nicole Ngoufack (ORCID: https://orcid.org/0009-0004-7163-2803)
- Carine Nguefeu Nkenfou-Tchinda (ORCID: https://orcid.org/0000-0002-6439-2133)
- Marceline Djuidje Ngounoue (ORCID: https://orcid.org/0000-0003-0031-3958)
- Celine Nguefeu Nkenfou
- Clifford Muluh
- Joelle Kadji Kameni
Institutions
- Université de Yaoundé I (CM)
- University of Maroua (CM)
- Centre International De Reference Chantal Biya (CM)
- Hanlim Pharm (South Korea) (KR)
- United Nations Children's Fund Cameroon (CM)
- Ministry of Higher Education (CM)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2024-09-13
- DOI
- https://doi.org/10.3389/fgene.2024.1447971
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00