Endogenous orexin and hyperacute autonomic responses after resuscitation in a preclinical model of cardiac arrest
Together, increased HR and elevated LF/HF ratio indicative of sympathetic arousal during a critical window (25-40 min) post-resuscitation are observed in animals with favorable outcomes. The orexin system appears to facilitate this hyperacute autonomic response post-<i>CA.</i>
Authors
- Romergryko G. Geocadin (ORCID: https://orcid.org/0000-0002-6618-5656)
- Hiren R. Modi (ORCID: https://orcid.org/0000-0003-1731-7111)
- Prachi Agarwal (ORCID: https://orcid.org/0000-0002-4439-6970)
- Payam Gharibani (ORCID: https://orcid.org/0000-0002-4546-0890)
- Nitish V. Thakor (ORCID: https://orcid.org/0000-0002-9981-9395)
- Sung‐Min Cho (ORCID: https://orcid.org/0000-0002-5132-0958)
- Yu Guo (ORCID: https://orcid.org/0000-0002-6802-0708)
Institutions
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Walter Reed Army Institute of Research (US)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2024-09-13
- DOI
- https://doi.org/10.3389/fnins.2024.1437464
- Citations
- 1
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 0.34