Longitudinal Analysis of Tear Cytokine Ratios in Association with Dry Eye Signs and Symptoms in the Dry Eye Assessment and Management (DREAM) Study
Improvement in some DED signs across one year correlated weakly with decreases in pro- to anti-inflammatory CRs, in alignment with the understanding of DED as inflammatory. CRs may provide greater insight than absolute tear cytokine concentrations as possible DED biomarkers. Additional studies that provide standardized clinical information and tear collection and analysis are needed to validate CRs in DED.
Authors
- Penny A. Asbell (ORCID: https://orcid.org/0000-0001-7583-7778)
- Yinxi Yu (ORCID: https://orcid.org/0000-0003-3820-1257)
- Cindy S. Zhao (ORCID: https://orcid.org/0000-0001-9925-2985)
- Yineng Chen (ORCID: https://orcid.org/0000-0003-4808-4525)
- Gui‐Shuang Ying (ORCID: https://orcid.org/0000-0002-5752-1355)
Institutions
- Bioengineering Center (RU)
- Smith-Kettlewell Eye Research Institute (US)
- Smith-Kettlewell Eye Research Institute (US)
- University of Pennsylvania (US)
- University of Memphis (US)
Publication Details
- Journal
- Current Eye Research
- Published
- 2024-09-12
- DOI
- https://doi.org/10.1080/02713683.2024.2398113
- Citations
- 2
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 1.09
Funders
- National Eye Institute