On the correction of spiral trajectories on a preclinical MRI scanner with a high‐performance gradient insert

This study aimed to examine different trajectory correction methods for spiral imaging on a preclinical scanner with high-performance gradients with respect to image quality in a phantom and in vivo. The gold standard method of measuring the trajectories in a separate experiment is compared to an isotropic delay-correction, a correction using the gradient system transfer function (GSTF), and a combination of the two. Three different spiral trajectories, with 96, 16, and three interleaves, are considered. The best image quality is consistently achieved when determining the trajectory in a separate phantom measurement. However, especially for the spiral with 96 interleaves, the other correction methods lead to almost comparable results. Remaining imperfections in the corrected gradient waveforms and trajectories are attributed to asymmetrically occurring undulations in the actual, generated gradients, suggesting that the underlying assumption of linearity is violated. In conclusion, images of sufficient quality can be acquired on preclinical small-animal scanners using spiral k-space trajectories without the need to carry out separate trajectory measurements each time. Depending on the trajectory, a simple isotropic delay-correction or a GSTF-based correction can provide images of similar quality.

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Publication Details

Journal
NMR in Biomedicine
Published
2024-09-12
DOI
https://doi.org/10.1002/nbm.5249
Citations
3
Primary Topic
Advanced MRI Techniques and Applications
Type
article
Field-Weighted Citation Impact
1.21

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article

On the correction of spiral trajectories on a preclinical MRI scanner with a high‐performance gradient insert

Jürgen E. Schneider, Tobias Wech, Herbert Köstler, Jordan H. Boyle et al.
3 citations
NMR in Biomedicine
Advanced MRI Techniques and Applications
1.21
article

On the correction of spiral trajectories on a preclinical MRI scanner with a high‐performance gradient insert

Jürgen E. Schneider, Tobias Wech, Herbert Köstler, Jordan H. Boyle, Irvin Teh, Hannah Scholten, Sean S. Smart, S. Köhler
article en
3 citations

Abstract

This study aimed to examine different trajectory correction methods for spiral imaging on a preclinical scanner with high-performance gradients with respect to image quality in a phantom and in vivo. The gold standard method of measuring the trajectories in a separate experiment is compared to an isotropic delay-correction, a correction using the gradient system transfer function (GSTF), and a combination of the two. Three different spiral trajectories, with 96, 16, and three interleaves, are considered. The best image quality is consistently achieved when determining the trajectory in a separate phantom measurement. However, especially for the spiral with 96 interleaves, the other correction methods lead to almost comparable results. Remaining imperfections in the corrected gradient waveforms and trajectories are attributed to asymmetrically occurring undulations in the actual, generated gradients, suggesting that the underlying assumption of linearity is violated. In conclusion, images of sufficient quality can be acquired on preclinical small-animal scanners using spiral k-space trajectories without the need to carry out separate trajectory measurements each time. Depending on the trajectory, a simple isotropic delay-correction or a GSTF-based correction can provide images of similar quality.

NMR in BiomedicineVol. 37(12)
University of Leeds (GB), University of Oxford (GB), Universitätsklinikum Würzburg (DE), Bruker (Germany) (DE), Delft University of Technology (NL)
British Heart Foundation, The Wellcome Trust DBT India Alliance, Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg
Openalex Percentile: Top 20%
Advanced MRI Techniques and Applications
1.21
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