Clinical and Laboratory Characteristics in Children Infected with Coronavirus Disease- 2019 in Iran

Background: Timely diagnosis and examination of clinical findings of children with COVID-19 are important for treatment and control. Objective: The purpose of this research is to determine the clinical and laboratory findings of children with COVID-19. Methods: A total of 850 children with a suspected diagnosis of COVID-19 in 2021 were considered according to the HIS. Based on PCR, a total of 52 children were confirmed positive for COVID-19. Statistical analysis was done using the SPSS 23.0, the ANOVA, and the t-test (p < 0.05). Results: Fever (73.10%) was the most common symptom. Difficult breathing (23.10%), shortness of breath (13.50%), required mechanical ventilation (11.50%), deaths (11.50%), genetic disorders (7.70%), diabetes (7.70%), WBC in admiration (7.0; 5.25, 10.05), lymphocytes (47.0; 29.00, 66.50), neutrophil (50.00; 29.00, 66.50), saturation O2 (87.37±13.58) and RR (37.41±14.04) were significantly correlated with the ICU admission (p<0.05). Conclusion: Differences between the rate of comorbidities, and clinical and paraclinical features, were significant between ICU and non-ICU patients. Examining underlying diseases in children is very important according to their clinical manifestations. Also, clinical and laboratory characteristics of disorders should be done immediately for children's early treatment.