Targeted Drug Delivery with Lipid-based Nanoparticles: Innovations for Improved Cancer Therapy
The capability of lipid-based nanoparticles (LBNs) to revolutionise cancer therapy is examined in this article. The potential of lipid-based nanoparticles (LBNs) to revolutionise cancer therapy is examined in this article. Before moving on to the formulation, characterization, and therapeutic applications of LBN, a brief discussion of the importance of targeted drug delivery is given. Liposomal delivery systems (LBNs), incorporating solid lipid nanoparticles (SLNs), liposomes and nanostructured lipid carriers, offer a versatile platform for accurate drug delivery (NLCs). The article discusses the potential of liquid nanoparticles (LBNs) in cancer therapy, highlighting their stability, storage, and techniques like reverse phase evaporation, thin-film hydration, and microemulsions. It also explores their physical characteristics, drug release studies, and role in tailored treatments. The review highlights manufacturing challenges and regulatory concerns while highlighting the evolving field of LBN applications.
Authors
- Shikha Baghel Chauhan (ORCID: https://orcid.org/0000-0002-1569-213X)
- Aritra Saha (ORCID: https://orcid.org/0000-0003-2748-196X)
- Indu Singh (ORCID: https://orcid.org/0000-0002-9038-4364)
Institutions
- Amity University (IN)
Publication Details
- Journal
- Nanoscience & Nanotechnology-Asia
- Published
- 2024-09-13
- DOI
- https://doi.org/10.2174/0122106812316387240822075859
- Citations
- 4
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.69