Single-cell sequencing delineates T-cell clonality and pathogenesis of the parapsoriasis disease group
These data position polyclonal small- and large-plaque parapsoriasis lesions as a separate disease entity that characteristically harbors a so far undescribed innate lymphoid cell population. We thus propose a new term, "polyclonal parapsoriasis en plaque", for this kind of lesion because they can be clearly differentiated from early- and advanced-stage MF, psoriasis, and AD on several cellular and molecular levels.
Authors
- Johannes Griss (ORCID: https://orcid.org/0000-0003-2206-9511)
- Christine Bangert (ORCID: https://orcid.org/0000-0003-3392-6590)
- Natalia Alkon (ORCID: https://orcid.org/0000-0002-0336-5318)
- Patrick M. Brunner (ORCID: https://orcid.org/0000-0002-3488-3345)
- Emry R. Cohenour
- Wolfgang Michael Bauer (ORCID: https://orcid.org/0000-0002-0155-1176)
- Katharina Rindler (ORCID: https://orcid.org/0000-0002-2142-8490)
- Wolfgang Weninger (ORCID: https://orcid.org/0000-0003-3133-8699)
- Sumanth Chennareddy (ORCID: https://orcid.org/0000-0002-3289-0592)
- Constanze Jonak (ORCID: https://orcid.org/0000-0002-2347-436X)
- Georg Stingl (ORCID: https://orcid.org/0000-0003-3843-7841)
- J. Ruggiero
Institutions
- Medical University of Vienna (AT)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology
- Published
- 2024-09-13
- DOI
- https://doi.org/10.1016/j.jaci.2024.09.004
- Citations
- 10
- Primary Topic
- Entomopathogenic Microorganisms in Pest Control
- Type
- article
- Field-Weighted Citation Impact
- 5.40
Funders
- Austrian Science Fund