USP7 regulates growth and maintains the stemness of p53-mutant colorectal cancer cells via stabilizing of mutant p53
Taken together, our findings demonstrated that USP7 involved in the modulation of CCSCs stemness, as well as a critical target for clinical treatment of cancers with different p53 mutations.
Authors
- Jie Pan
- Xue Li (ORCID: https://orcid.org/0000-0003-2774-9110)
- Pengcheng Zheng (ORCID: https://orcid.org/0000-0003-2867-9847)
Institutions
- Kunming University of Science and Technology (CN)
- First People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2024-09-12
- DOI
- https://doi.org/10.3389/fonc.2024.1427663
- Citations
- 5
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Shanghai Jiao Tong University
- Ruijin Hospital
- School of Medicine, Shanghai Jiao Tong University