Preparation of transferrin-targeted temozolomide nano-micelles and their anti-glioma effect
TMZ-loaded nano-micelles demonstrated a gradual release profile and significantly enhanced inhibitory effects on human glioma U251 cells compared to TMZ alone. The findings suggest that TMZ-loaded PEG-PLA nano-micelles may offer a more effective therapeutic approach for glioma treatment.
Authors
- Jun Qing Yu (ORCID: https://orcid.org/0000-0001-5008-2153)
- Yonghua Xue
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2024-09-13
- DOI
- https://doi.org/10.7717/peerj.17979
- Citations
- 4
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.74