CD206 accelerates hepatocellular carcinoma progression by regulating the tumour immune microenvironment and increasing M2-type polarisation of tumour-associated macrophages and inflammation factor expression
The overexpression of CD206 accelerates the progression of HCC and changes the tumour immune microenvironment. The high expression of CD206 in HCC increases the M2-type polarisation of TAMs and induces the expression of both TGF-β and IL-6 in tumour tissues and serum, thereby promoting HCC progression.
Authors
- Yinglin Li (ORCID: https://orcid.org/0000-0002-2732-3040)
- Li Bai (ORCID: https://orcid.org/0000-0003-4391-2248)
- Yalin Han (ORCID: https://orcid.org/0000-0002-2090-0917)
- Zhiyuan Mao (ORCID: https://orcid.org/0000-0003-1817-5469)
Institutions
- Chinese PLA General Hospital (CN)
- 307th Hospital of Chinese People’s Liberation Army (CN)
- Air Force General Hospital PLA (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2024-09-13
- DOI
- https://doi.org/10.1007/s12672-024-01309-1
- Citations
- 2
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.48