Use of anamorelin hydrochloride in a patient with lung cancer-related cachexia undergoing chemoradiotherapy: A case report

This report describes the case of a 59-year-old man with poorly differentiated lung adenocarcinoma and cachexia who completed chemoradiation therapy for stage III lung cancer following the administration of anamorelin. Anamorelin, a ghrelin receptor agonist, effectively improved his appetite and performance status, thereby enabling the continuation of treatment. The role of anamorelin in enhancing appetite during acute-phase treatment is promising; however, further studies must be conducted to elucidate its interaction with chemoradiation therapy. This case report highlights the potential of anamorelin as a therapeutic option for the management of cancer-related cachexia during curative treatment for lung cancer.

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Journal
Current Problems in Cancer Case Reports
Published
2024-09-13
DOI
https://doi.org/10.1016/j.cpccr.2024.100322
Primary Topic
Nutrition and Health in Aging
Type
article
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article

Use of anamorelin hydrochloride in a patient with lung cancer-related cachexia undergoing chemoradiotherapy: A case report

Kei Nakashima, Haruka Fujioka, Ayumu Otsuki, Reina Idemitsu et al.
Current Problems in Cancer Case Reports
Nutrition and Health in Aging
article

Use of anamorelin hydrochloride in a patient with lung cancer-related cachexia undergoing chemoradiotherapy: A case report

Kei Nakashima, Haruka Fujioka, Ayumu Otsuki, Reina Idemitsu, Yasuhiro Morimoto, Hiroyuki Ito, Kentaro Tochigi, Shigenori Yamamoto, Nana Munakata, Taiki Kawai
article en

Abstract

This report describes the case of a 59-year-old man with poorly differentiated lung adenocarcinoma and cachexia who completed chemoradiation therapy for stage III lung cancer following the administration of anamorelin. Anamorelin, a ghrelin receptor agonist, effectively improved his appetite and performance status, thereby enabling the continuation of treatment. The role of anamorelin in enhancing appetite during acute-phase treatment is promising; however, further studies must be conducted to elucidate its interaction with chemoradiation therapy. This case report highlights the potential of anamorelin as a therapeutic option for the management of cancer-related cachexia during curative treatment for lung cancer.

Current Problems in Cancer Case ReportsVol. 16
SHOWA Medical University (JP), Kameda Medical Center (JP), Obihiro Kosei General Hospital (JP)
Good health and well-being
Openalex Percentile: Top 79%
Nutrition and Health in Aging
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Use of anamorelin hydrochloride in a patient with lung cancer-related cachexia undergoing chemoradiotherapy: A case report — Kei Nakashima, Haruka Fujioka, et al. · Current Problems in Cancer Case Reports (2024) | TGRS Research Map | TGRS