Exosomal transcript cargo and functional correlation with HNSCC patients’ survival
Overall, our study demonstrates that HPV-positive and HPV-negative cells' exosomes carried differential transcripts cargo that may be related to pathways associated with neurological disorders. Additionally, the altered transcripts identified have clinical relevance, correlating with patient survival in HNSCC, thereby highlighting their potential as biomarkers and as therapeutic targets.
Authors
- Joni Yadav
- Arun Chhokar
- Apoorva Chaudhary
- Nikita Aggarwal
- Divya Janjua (ORCID: https://orcid.org/0009-0005-8057-1405)
- Anna Senrung (ORCID: https://orcid.org/0000-0003-1050-9671)
- Udit Joshi
- Alok C. Bharti (ORCID: https://orcid.org/0000-0002-5996-2832)
- Chetkar Chandra Keshavam
- Tanya Tripathi
Institutions
- University of Delhi (IN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-09-13
- DOI
- https://doi.org/10.1186/s12885-024-12759-9
- Citations
- 5
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Indian Council of Medical Research
- Council of Scientific and Industrial Research, India
- University Grants Commission
- University of Delhi