Placentation abnormalities related to the assisted reproductive technologies

Placentation abnormalities resulting from using assisted reproductive technologies (ART) is a pressing global obstetrical issue due to complications associated with the pathology: bleeding during pregnancy, postpartum hemorrhage, higher number of cesarean sections, perinatal and maternal morbidity and mortality. This pathology rate tends to increase also due to higher number of pregnancies achieved via in vitro fertilization (IVF). In this regard, we decided to find out the key risk factors for developing this pathology, identify new international data on placentation abnormalities, ART impact on this disease, since ART have been increasingly used to achieve pregnancy in women, both in Russia and abroad. Recent studies have proven the unique morphological structure of the placental hematopoietic barrier in post-IVF women as well as an increased incidence of placentation abnormalities, placenta accreta and premature abruption in comparison with spontaneous pregnancy.