Effect of concentration, temperature, and time on the stability of hepatitis C virus nucleic acid in serum
Previously, there were few reports about the influence of different concentrations of sample nucleic acid on the stability of samples at various temperatures and times in various literatures. Therefore, it is necessary to analyze the influence of concentration factors on the stability of samples and test results at different storage times and temperatures. This study took the concentration of hepatitis C virus nucleic acid as the research object to further understand the stability of hepatitis C virus nucleic acid test samples under various storage conditions, to provide data reference for the treatment of hepatitis C virus nucleic acid and RNA test samples before clinical laboratory test, and provide guidance and help for the improvement of laboratory quality control.
Authors
- Yixuan Wang (ORCID: https://orcid.org/0000-0002-2518-0699)
- Jingfeng Bi (ORCID: https://orcid.org/0000-0002-4114-4372)
- Boan Li (ORCID: https://orcid.org/0000-0003-1999-9398)
- Xue Xu
- Shu-wen Yang
- Fan Jia
- Ya-pei Wang
- Wei J. Wang (ORCID: https://orcid.org/0000-0002-4848-7394)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Chinese PLA General Hospital (CN)
Publication Details
- Journal
- Microbiology Spectrum
- Published
- 2024-09-13
- DOI
- https://doi.org/10.1128/spectrum.00769-24
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00