Effect of concentration, temperature, and time on the stability of hepatitis C virus nucleic acid in serum

Previously, there were few reports about the influence of different concentrations of sample nucleic acid on the stability of samples at various temperatures and times in various literatures. Therefore, it is necessary to analyze the influence of concentration factors on the stability of samples and test results at different storage times and temperatures. This study took the concentration of hepatitis C virus nucleic acid as the research object to further understand the stability of hepatitis C virus nucleic acid test samples under various storage conditions, to provide data reference for the treatment of hepatitis C virus nucleic acid and RNA test samples before clinical laboratory test, and provide guidance and help for the improvement of laboratory quality control.

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Publication Details

Journal
Microbiology Spectrum
Published
2024-09-13
DOI
https://doi.org/10.1128/spectrum.00769-24
Primary Topic
Hepatitis C virus research
Type
article
Field-Weighted Citation Impact
0.00
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article

Effect of concentration, temperature, and time on the stability of hepatitis C virus nucleic acid in serum

Yixuan Wang, Jingfeng Bi, Boan Li, Xue Xu et al.
Microbiology Spectrum
Hepatitis C virus research
article

Effect of concentration, temperature, and time on the stability of hepatitis C virus nucleic acid in serum

Yixuan Wang, Jingfeng Bi, Boan Li, Xue Xu, Shu-wen Yang, Fan Jia, Ya-pei Wang, Wei J. Wang
article en

Abstract

Previously, there were few reports about the influence of different concentrations of sample nucleic acid on the stability of samples at various temperatures and times in various literatures. Therefore, it is necessary to analyze the influence of concentration factors on the stability of samples and test results at different storage times and temperatures. This study took the concentration of hepatitis C virus nucleic acid as the research object to further understand the stability of hepatitis C virus nucleic acid test samples under various storage conditions, to provide data reference for the treatment of hepatitis C virus nucleic acid and RNA test samples before clinical laboratory test, and provide guidance and help for the improvement of laboratory quality control.

Microbiology SpectrumVol. 12(10)
Shandong University of Traditional Chinese Medicine (CN), Chinese PLA General Hospital (CN)
Good health and well-being
Openalex Percentile: Top 75%
Hepatitis C virus research
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Effect of concentration, temperature, and time on the stability of hepatitis C virus nucleic acid in serum — Yixuan Wang, Jingfeng Bi, et al. · Microbiology Spectrum (2024) | TGRS Research Map | TGRS