Lock out SIRT4

The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.

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Publication Details

Journal
eLife
Published
2024-09-13
DOI
https://doi.org/10.7554/elife.102355
Primary Topic
Sirtuins and Resveratrol in Medicine
Type
article
Field-Weighted Citation Impact
0.00
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article

Lock out SIRT4

Zhongjun Zhou, Kaiqiang Zhao
eLife
Sirtuins and Resveratrol in Medicine
article

Lock out SIRT4

Zhongjun Zhou, Kaiqiang Zhao
article en

Abstract

The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.

eLifeVol. 13
University of Hong Kong (HK)
Good health and well-being
Openalex Percentile: Top 80%
Sirtuins and Resveratrol in Medicine
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Lock out SIRT4 — Zhongjun Zhou, Kaiqiang Zhao · eLife (2024) | TGRS Research Map | TGRS