Erythropoietin Reduces Inflammation, Oxidative Stress, and Apoptosis in a Rat Model of Bleomycin-Induced Idiopathic Pulmonary Fibrosis
The reduced expression of COX-2, i-NOS, MMP-9, EPO-R, and i-NOS in the lung tissues of animals treated with EPO indicates the anti-inflammatory, antioxidant and antiapoptotic action of erythropoietin, suggesting its potential therapeutic role in pulmonary fibrosis.
Authors
- Drosos Tsavlis (ORCID: https://orcid.org/0000-0001-7225-3646)
- Soultana Meditskou (ORCID: https://orcid.org/0000-0001-7929-9110)
- Κonstantinos Porpodis (ORCID: https://orcid.org/0000-0001-7215-2191)
- Doxakis Anestakis (ORCID: https://orcid.org/0000-0001-8004-7666)
- Kalliopi Domvri (ORCID: https://orcid.org/0000-0002-4812-9108)
- Evangelia Spandou (ORCID: https://orcid.org/0000-0001-9139-0427)
- Anna Tzoumaka
- Stamatia Papoutsopoulou (ORCID: https://orcid.org/0000-0001-6665-8508)
- Konstantina Symeonidoy
Institutions
- University of Thessaly (GR)
- Aristotle University of Thessaloniki (GR)
- University of Cyprus (CY)
- G. Papanikolaou General Hospital (GR)
Publication Details
- Journal
- Journal of Personalized Medicine
- Published
- 2024-09-13
- DOI
- https://doi.org/10.3390/jpm14090972
- Citations
- 3
- Primary Topic
- Erythropoietin and Anemia Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.36