Determinant of 30-Day Mortality of Pulmonary Legionellosis: Do Coinfections Matter?
We retrospectively reviewed 64 cases of cancer with pulmonary legionellosis (<i>Legionella pneumophila</i> in 73%). Nearly all patients received <i>Legionella</i>-active antibiotics, yet 30-day mortality was 23%. Independent predictors of 30-day mortality were hyponatremia, bilateral lung involvement, and Sequential Organ Failure Assessment score ≥5. Lung coinfections were common (31%) but did not significantly increase mortality.
Authors
- Takahiro Matsuo (ORCID: https://orcid.org/0000-0001-9389-0628)
- Jeffrey J. Tarrand (ORCID: https://orcid.org/0000-0002-0183-9946)
- Ying Jiang (ORCID: https://orcid.org/0000-0002-1309-9922)
- Sebastian Wurster (ORCID: https://orcid.org/0000-0002-7784-7256)
- Dimitrios P. Kontoyiannis (ORCID: https://orcid.org/0000-0002-8051-2940)
- Scott E. Evans (ORCID: https://orcid.org/0000-0003-4503-0644)
Institutions
- The University of Texas MD Anderson Cancer Center (US)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1093/ofid/ofae529
- Citations
- 1
- Primary Topic
- Legionella and Acanthamoeba research
- Type
- article
- Field-Weighted Citation Impact
- 0.62