Advanced Quantitative MRI Unveils Microstructural Thalamic Changes Reflecting Disease Progression in Multiple Sclerosis
These findings offer deeper insights into thalamic pathology in PwMS, emphasizing the clinical relevance of thalamic damage and its link to disease progression. Advanced qMRI biomarkers show promising potential in guiding interventions aimed at mitigating thalamic neurodegenerative processes.
Authors
- Xinjie Chen (ORCID: https://orcid.org/0000-0002-3683-6489)
- Alessandro Cagol (ORCID: https://orcid.org/0000-0002-7703-0553)
- Antoine Lutti (ORCID: https://orcid.org/0000-0003-3281-5477)
- Jens Kühle (ORCID: https://orcid.org/0000-0002-6963-8892)
- Po‐Jui Lu (ORCID: https://orcid.org/0000-0001-6031-6865)
- Ludwig Kappos (ORCID: https://orcid.org/0000-0003-4175-5509)
- Matthias Weigel (ORCID: https://orcid.org/0000-0002-4910-1414)
- Maria Pia Sormani (ORCID: https://orcid.org/0000-0001-6892-104X)
- Muhamed Baraković (ORCID: https://orcid.org/0000-0001-8557-9223)
- Mario Ocampo‐Pineda (ORCID: https://orcid.org/0000-0003-2239-7355)
- Pasquale Calabrese (ORCID: https://orcid.org/0000-0003-3347-5187)
- Cristina Granziera (ORCID: https://orcid.org/0000-0002-4917-8761)
- Lester Melie‐García (ORCID: https://orcid.org/0000-0001-5602-8916)
Institutions
- University Hospital of Basel (CH)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2024-09-13
- DOI
- https://doi.org/10.1212/nxi.0000000000200299
- Citations
- 12
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.10
Funders
- National Science Foundation
- Eli Lilly and Company
- Sanofi
- Biogen
- Teva Pharmaceutical Industries
- Alexion Pharmaceuticals
- Celgene
- F. Hoffmann-La Roche
- Universität Basel
- TG Therapeutics
- International Progressive MS Alliance
- National Research Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Shionogi
- Fondation Roger de Spoelberch
- H. Lundbeck A/S
- Innosuisse - Schweizerische Agentur für Innovationsförderung
- Genentech
- EMD Serono