Ovarian luteoma masses in pregnancy: an uncommon cause of virilisation

Pregnancy luteoma is a benign ovarian tumour that presents during pregnancy and regresses spontaneously post partum. The mass may secrete androgenic hormones which can result in virilisation of mother and female foetus. Clinical presentation of pregnancy luteoma is varied from asymptomatic to significant virilisation. We present two cases of ovarian luteomas identified incidentally at caesarean section. The first case had marked hirsutism, while the second case had mild acne. Both foetuses were male and appeared unaffected at birth. Where maternal virilisation is identified during pregnancy, differential diagnoses including pregnancy luteoma should be considered.

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Publication Details

Journal
BMJ Case Reports
Published
2024-09-01
DOI
https://doi.org/10.1136/bcr-2024-261239
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
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article

Ovarian luteoma masses in pregnancy: an uncommon cause of virilisation

Isabella Stewart, Emily Twidale
BMJ Case Reports
Ovarian cancer diagnosis and treatment
article

Ovarian luteoma masses in pregnancy: an uncommon cause of virilisation

Isabella Stewart, Emily Twidale
article en

Abstract

Pregnancy luteoma is a benign ovarian tumour that presents during pregnancy and regresses spontaneously post partum. The mass may secrete androgenic hormones which can result in virilisation of mother and female foetus. Clinical presentation of pregnancy luteoma is varied from asymptomatic to significant virilisation. We present two cases of ovarian luteomas identified incidentally at caesarean section. The first case had marked hirsutism, while the second case had mild acne. Both foetuses were male and appeared unaffected at birth. Where maternal virilisation is identified during pregnancy, differential diagnoses including pregnancy luteoma should be considered.

BMJ Case ReportsVol. 17(9)
Northern Hospital (AU)
Good health and well-being
Openalex Percentile: Top 78%
Ovarian cancer diagnosis and treatment
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