Blackcurrant ( <i>Ribes nigrum</i> L.) improves cholinergic signaling and protects against chronic Scopolamine-induced memory impairment in mice
Findings suggest that blackcurrant and Donepezil, either alone or in combination, have anti-amnesic effects by modulating cholinergic system enzymes and improving the redox profile. Therefore, blackcurrant could be used as a natural supplement for the prevention and treatment of memory impairment in neurodegenerative diseases.
Authors
- Naiara Stefanello (ORCID: https://orcid.org/0000-0002-9190-8465)
- Jessié Martins Gutierres (ORCID: https://orcid.org/0000-0002-9574-4007)
- Karine Paula Reichert (ORCID: https://orcid.org/0000-0003-2575-5891)
- Pauline da Costa
- Ivana Beatrice Mânica da Cruz (ORCID: https://orcid.org/0000-0003-3008-6899)
- Thauan Faccin Lopes (ORCID: https://orcid.org/0000-0001-9321-2616)
- Jucimara Baldissarelli (ORCID: https://orcid.org/0000-0002-1114-0063)
- Charles Elias Assmann (ORCID: https://orcid.org/0000-0002-3524-3446)
- Vera Maria Morsch (ORCID: https://orcid.org/0000-0002-5381-4556)
- Nathieli Bianchin Bottari (ORCID: https://orcid.org/0000-0003-0294-9650)
- Maria Rosa Chitolina Schetinger (ORCID: https://orcid.org/0000-0002-5240-8935)
- Vanessa Valéria Miron (ORCID: https://orcid.org/0000-0001-5266-7534)
- Fermina Francesca A Vargas
Institutions
- Universidade Federal de Pelotas (BR)
- Universidade Federal de Alfenas (BR)
- Universidade Federal de Santa Maria (BR)
Publication Details
- Journal
- Journal of Psychopharmacology
- Published
- 2024-09-12
- DOI
- https://doi.org/10.1177/02698811241273776
- Citations
- 6
- Primary Topic
- Medicinal Plants and Neuroprotection
- Type
- article
- Field-Weighted Citation Impact
- 4.30