Clinical features and immunotherapy outcomes in antibody-negative autoimmune encephalitis: a retrospective case–control study
Antibody-positive AE patients manifested a more diverse symptom spectrum, elevated serum IgG concentrations and CSF leukocyte counts, and superior responses to immunotherapy. In contrast, antibody-negative AE patients demonstrated more severe blood-brain barrier dysfunction, as evidenced by higher CSF total protein concentrations and albumin quotients.
Authors
- Lihong Su (ORCID: https://orcid.org/0000-0002-2992-5942)
- Xingyu Chen (ORCID: https://orcid.org/0000-0002-9284-4950)
- Qingwei Yang
- Weiwei Gao (ORCID: https://orcid.org/0000-0002-1451-3312)
- Shouyue Jin (ORCID: https://orcid.org/0000-0003-2289-890X)
- Renjing Zhu
- Jingjing She
Institutions
- Zhongshan Hospital of Xiamen University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2024-09-12
- DOI
- https://doi.org/10.3389/fneur.2024.1464165
- Citations
- 1
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.37