Antibiotic-induced dysbiosis in the SCIME™ recapitulates microbial community diversity and metabolites modulation of in vivo disease
This alteration in microbial community and metabolites production mimicks <i>in vivo</i> canine dysbiosis patterns. A novel dynamic <i>in vitro</i> model simulating canine antibiotic-induced dysbiosis, capable of reproducing microbial and metabolic changes observed <i>in vivo</i>, has been developed and is suitable for testing the effects of nutritional changes.
Authors
- Benedetta Bachetti
- Elena Dalle Vedove (ORCID: https://orcid.org/0000-0001-7185-2188)
- Maria Veronica Giordano (ORCID: https://orcid.org/0000-0001-6562-8147)
- Francesco Di Pierro (ORCID: https://orcid.org/0000-0001-6654-8675)
- Alessia Benvenga
- Marcella Massimini (ORCID: https://orcid.org/0000-0001-7204-6495)
- Gianluca Nicolai
Institutions
- University of Insubria (IT)
- University of Teramo (IT)
- Velleja Research (IT)
- Regione Puglia (IT)
- I.R.C.C.S. Oasi Maria SS (IT)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2024-09-12
- DOI
- https://doi.org/10.3389/fmicb.2024.1455839
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00