Standardization and quality assessment for human intestinal organoids
To enhance the practical application of intestinal organoids, it is imperative to establish standardized guidelines. This proposed standardization outlines a comprehensive framework to ensure consistency and reliability in the development, characterization, and application of intestinal organoids. The recommended guidelines encompass crucial parameters, including culture conditions, critical quality attributes, quality control measures, and functional assessments, aimed at fostering a standardized approach across diverse research initiatives. The implementation of these guidelines is anticipated to significantly contribute to the reproducibility and comparability of results in the burgeoning field of intestinal organoid research.
Authors
- Dayeon Kwon
- Kyung Jin Lee
- Chihye Park (ORCID: https://orcid.org/0009-0004-7237-9547)
- Jongman Yoo (ORCID: https://orcid.org/0000-0003-4294-7051)
- Hanbyeol Lee (ORCID: https://orcid.org/0000-0001-9671-315X)
- Sungin Lee (ORCID: https://orcid.org/0000-0002-4260-2160)
- Sooyeon Jeon (ORCID: https://orcid.org/0000-0003-4585-2111)
- S. J. Kim
- Cho‐Rok Jung
- Ji‐Seon Jeong (ORCID: https://orcid.org/0000-0002-9750-981X)
- Sun-Ju Ahn (ORCID: https://orcid.org/0000-0002-8325-2312)
- Hana Lee (ORCID: https://orcid.org/0000-0001-7782-5711)
- Ki Young Kim (ORCID: https://orcid.org/0000-0001-7868-2345)
- Seunghye Yang
- Mi-Young Son
Institutions
- Korea Research Institute of Standards and Science (KR)
- KoreaBio (KR)
- CHA University (KR)
- Korea Research Institute of Chemical Technology (KR)
- Korea Research Institute of Bioscience and Biotechnology (KR)
- Sungkyunkwan University (KR)
- Korea University of Science and Technology (KR)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2024-09-12
- DOI
- https://doi.org/10.3389/fcell.2024.1383893
- Citations
- 16
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 4.52
Funders
- Ministry of Trade, Industry and Energy
- Ministry of Food and Drug Safety
- Korea Health Industry Development Institute
- Korea Research Institute of Bioscience and Biotechnology
- Ministry of Science and ICT, South Korea