Identification of cellular senescence-related genes and immune cell infiltration characteristics in intervertebral disc degeneration
Senescence-related genes play a key role in the development and occurrence of IDD. IGFBP3 and NQO1 are strongly correlated with immune infiltration in the IDD and could become novel therapeutic targets that prevent the progression of IDD.
Authors
- Yuqing Jiang (ORCID: https://orcid.org/0000-0003-3638-7828)
- Muyi Wang (ORCID: https://orcid.org/0000-0003-1766-827X)
- Xin Wang (ORCID: https://orcid.org/0000-0001-7467-6060)
- Dong Zhou (ORCID: https://orcid.org/0000-0001-6075-4072)
- Yifei Shen (ORCID: https://orcid.org/0000-0001-7174-4793)
- Hao Wang (ORCID: https://orcid.org/0000-0001-5461-0689)
Institutions
- Changzhou No.2 People's Hospital (CN)
- Hangzhou Children's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-09-12
- DOI
- https://doi.org/10.3389/fimmu.2024.1439976
- Citations
- 7
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 2.97