Pickle water ameliorates castor oil-induced diarrhea in mice by regulating the homeostasis of the gut microbiota and intestinal mucosal barrier
Collectively, dietary PW administration ameliorates Castor oil-induced diarrhea by restoring tight junctions between intestinal mucosal cells, suppressing oxidative stress, and regulating the composition of intestinal flora. These findings suggest that PW may be a promising strategy for managing diarrhea.
Authors
- Tian Zhou (ORCID: https://orcid.org/0000-0001-8557-3091)
- Xing Wang (ORCID: https://orcid.org/0000-0003-0106-202X)
- Maoting Zhou
- Xianghong Hu
- Dongmei Long
- Yu Wang (ORCID: https://orcid.org/0000-0003-2420-3585)
Institutions
- North Sichuan Medical University (CN)
- Zhengzhou Children's Hospital (CN)
- Nanchong Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2024-09-12
- DOI
- https://doi.org/10.3389/fnut.2024.1455091
- Citations
- 3
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.39