Identification of zinc finger MIZ-type containing 2 as an oncoprotein enhancing NAD-dependent protein deacetylase sirtuin-1 deacetylase activity to regulate Wnt and Hippo pathways in non-small-cell lung cancer
ZMIZ2 promotes the malignant phenotype of lung cancer by regulating Wnt/Hippo pathways through SIRT1, providing an experimental basis for discovering novel biomarkers and developing tumor-targeted drugs.
Authors
- Xuezhu Rong (ORCID: https://orcid.org/0000-0001-6623-5927)
- Xinmiao Yu (ORCID: https://orcid.org/0000-0002-4268-5672)
- Xuyong Lin
- Xueting Gan
- Yuheng Feng
- Qiang Han
- Yang Liu
Institutions
- First Hospital of China Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Cellular & Molecular Biology Letters
- Published
- 2024-09-12
- DOI
- https://doi.org/10.1186/s11658-024-00636-z
- Citations
- 5
- Primary Topic
- Hippo pathway signaling and YAP/TAZ
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- National Natural Science Foundation of China