Evaluation of Electrolyte Levels in Patients with Acute Coronary Syndrome

Objective: The study aims to assess electrolyte imbalances in patients diagnosed with acute coronarysyndrome (ACS) and to explore whether these imbalances are associated with poor clinical outcomes in ACS.Study Design: Cross-sectional analytical study.Place and Duration of Study: The study was conducted at the Department of Cardiology, Mardan MedicalComplex Mardan, Pakistan from September 2023 to December 2023.Methods: A cross-sectional study on 360 patients was conducted using the WHO sample size calculator.Patients from both genders were included in this study. Demographic information of patients was obtained.Serum electrolyte levels were done from the hospital's laboratory. Information was collected in predesignedproforma. Sampling was done via non-probability convenient sampling. Informed consent was taken from allpatients, ensuring confidentiality and the fact that there will be no risk to the patients who are taking part in this study.Results: Unstable angina was found in 60 (16.7%), in Non-ST-elevation myocardial infarction (NSTEMI) 154(42.8%) and in ST elevation myocardial infarction (STEMI) 146 (40.6%) patients. Hyponatremia was found to bein 108 (30%) patients, and it was associated in causing heart failure in around 58 (16.11%) patients.Hypokalemia was present in 65 (18%) patients and showed VT in 28 (7.77%) cases. Hypomagnesemia (31.9%)caused heart failure in 30 (8.33%) patients followed by VT in 26 (7.22%), cardiogenic shock in 24 (6.66%). Allelectrolyte disturbances of the current study carried statistical significance in causing complications i.e. P-value<0.001.Conclusion: We concluded that electrolyte disturbances are common in patients with acute coronarysyndrome, and they carry adverse outcomes with respect to ACS related complications and mortality.

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Publication Details

Journal
Life and Science
Published
2024-08-15
DOI
https://doi.org/10.37185/lns.1.1.624
Primary Topic
Electrolyte and hormonal disorders
Type
article
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article

Evaluation of Electrolyte Levels in Patients with Acute Coronary Syndrome

Muhammad Farooq, Noor ul Hadi, Amna Saleem, Jehandad Khan
Life and Science
Electrolyte and hormonal disorders
article

Evaluation of Electrolyte Levels in Patients with Acute Coronary Syndrome

Muhammad Farooq, Noor ul Hadi, Amna Saleem, Jehandad Khan
article en

Abstract

Objective: The study aims to assess electrolyte imbalances in patients diagnosed with acute coronarysyndrome (ACS) and to explore whether these imbalances are associated with poor clinical outcomes in ACS.Study Design: Cross-sectional analytical study.Place and Duration of Study: The study was conducted at the Department of Cardiology, Mardan MedicalComplex Mardan, Pakistan from September 2023 to December 2023.Methods: A cross-sectional study on 360 patients was conducted using the WHO sample size calculator.Patients from both genders were included in this study. Demographic information of patients was obtained.Serum electrolyte levels were done from the hospital's laboratory. Information was collected in predesignedproforma. Sampling was done via non-probability convenient sampling. Informed consent was taken from allpatients, ensuring confidentiality and the fact that there will be no risk to the patients who are taking part in this study.Results: Unstable angina was found in 60 (16.7%), in Non-ST-elevation myocardial infarction (NSTEMI) 154(42.8%) and in ST elevation myocardial infarction (STEMI) 146 (40.6%) patients. Hyponatremia was found to bein 108 (30%) patients, and it was associated in causing heart failure in around 58 (16.11%) patients.Hypokalemia was present in 65 (18%) patients and showed VT in 28 (7.77%) cases. Hypomagnesemia (31.9%)caused heart failure in 30 (8.33%) patients followed by VT in 26 (7.22%), cardiogenic shock in 24 (6.66%). Allelectrolyte disturbances of the current study carried statistical significance in causing complications i.e. P-value<0.001.Conclusion: We concluded that electrolyte disturbances are common in patients with acute coronarysyndrome, and they carry adverse outcomes with respect to ACS related complications and mortality.

Life and ScienceVol. 5(3)
Abdul Wali Khan University Mardan (PK), Combined Military Hospital (PK)
Good health and well-being
Openalex Percentile: Top 72%
Electrolyte and hormonal disorders
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