Plasma cell granuloma middle ear: A rare lesion at a rare site

Plasma cell granuloma (PCG) is a rare non-neoplastic lesion, characterised by proliferation of immunoreactive polyclonal plasma cells present in a fibrous background. We present a case of 30 year male who presented with left sided otalgia, tinnitus and otorrhea along with mild conductive hearing loss. On CT scan a diagnosis of CSOM with granulation tissue was made however on histological examination, on microscopy with immunohistochemistry (IHC), it was reported as plasma cell granuloma of the middle ear. Middle ear plasma cell granuloma is a rare entity only few cases are reported in literature so far. Here, we will discuss clinical presentation, histological diagnosis with IHC and management of this rare entity at an unusual location along with review of literature.

Authors

Publication Details

Journal
Indian Journal of Pathology and Oncology
Published
2024-09-12
DOI
https://doi.org/10.18231/j.ijpo.2024.068
Citations
1
Primary Topic
IgG4-Related and Inflammatory Diseases
Type
article
Field-Weighted Citation Impact
0.47
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article

Plasma cell granuloma middle ear: A rare lesion at a rare site

Sujatha Poduval, Pretty Singh, Kavita Somani
1 citations
Indian Journal of Pathology and Oncology
IgG4-Related and Inflammatory Diseases
0.47
article

Plasma cell granuloma middle ear: A rare lesion at a rare site

Sujatha Poduval, Pretty Singh, Kavita Somani
article en
1 citations

Abstract

Plasma cell granuloma (PCG) is a rare non-neoplastic lesion, characterised by proliferation of immunoreactive polyclonal plasma cells present in a fibrous background. We present a case of 30 year male who presented with left sided otalgia, tinnitus and otorrhea along with mild conductive hearing loss. On CT scan a diagnosis of CSOM with granulation tissue was made however on histological examination, on microscopy with immunohistochemistry (IHC), it was reported as plasma cell granuloma of the middle ear. Middle ear plasma cell granuloma is a rare entity only few cases are reported in literature so far. Here, we will discuss clinical presentation, histological diagnosis with IHC and management of this rare entity at an unusual location along with review of literature.

Indian Journal of Pathology and OncologyVol. 11(3)
Good health and well-being
Openalex Percentile: Top 32%
IgG4-Related and Inflammatory Diseases
0.47
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