RAC1 serves as a prognostic factor and correlated with immune infiltration in liver hepatocellular carcinoma

These findings indicate that RAC1 expression promotes LIHC proliferation and migration and influences the landscape of immune cell infiltration in the tumor microenvironment. Based on these results, RAC1 is proposed as a potential prognostic biomarker for LIHC, associated with both cancer progression and tumor immune cell infiltration.

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Publication Details

Journal
Journal of Cancer Research and Clinical Oncology
Published
2024-09-12
DOI
https://doi.org/10.1007/s00432-024-05933-w
Citations
2
Primary Topic
Endoplasmic Reticulum Stress and Disease
Type
article
Field-Weighted Citation Impact
0.65

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article

RAC1 serves as a prognostic factor and correlated with immune infiltration in liver hepatocellular carcinoma

Lili Yang, Qingbo Wang, Aidong Gu, Yuan Li
2 citations
Journal of Cancer Research and Clinical Oncology
Endoplasmic Reticulum Stress and Disease
0.65
article

RAC1 serves as a prognostic factor and correlated with immune infiltration in liver hepatocellular carcinoma

Lili Yang, Qingbo Wang, Aidong Gu, Yuan Li
article en
2 citations

Abstract

These findings indicate that RAC1 expression promotes LIHC proliferation and migration and influences the landscape of immune cell infiltration in the tumor microenvironment. Based on these results, RAC1 is proposed as a potential prognostic biomarker for LIHC, associated with both cancer progression and tumor immune cell infiltration.

Journal of Cancer Research and Clinical OncologyVol. 150(9)
Nanjing University of Chinese Medicine (CN), Nanjing Second Hospital (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 32%
Endoplasmic Reticulum Stress and Disease
0.65
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