High-Risk HPV Detection in Paraffin-Embedded Tissue from Cervical Lesions
This study demonstrates that the Anyplex™ II hrHPV Detection kit, originally designed for cervical cancer screening, is also effective for hrHPV genotyping in histological analyses. This methodology offers a simpler and more cost-effective approach for cervical cancer risk stratification. Its implementation in clinical practice could enhance the detection of hrHPV in cervical lesions, thereby contributing to more precise diagnoses and potentially more informed treatment strategies.
Authors
- José Fonseca-Moutinho (ORCID: https://orcid.org/0000-0001-7157-3066)
- Ana Cristina Ramalhinho (ORCID: https://orcid.org/0000-0003-4783-665X)
- Vítor Caeiro (ORCID: https://orcid.org/0000-0002-1333-9404)
- Micaela Almeida (ORCID: https://orcid.org/0000-0002-4280-0765)
- Sofia Campelos (ORCID: https://orcid.org/0000-0002-6847-5630)
- Luiza Breitenfeld (ORCID: https://orcid.org/0000-0001-8550-1645)
- Paula Roberta da Silva Pestana (ORCID: https://orcid.org/0000-0001-9312-8713)
- João Vale (ORCID: https://orcid.org/0000-0002-7397-0839)
- Lara Silva (ORCID: https://orcid.org/0009-0006-8412-137X)
- Cíntia Sousa
- Diana Costa
Institutions
- University of Beira Interior (PT)
- Hospital Center of Cova da Beira (PT)
- i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto (PT)
Publication Details
- Journal
- Pharmaceuticals
- Published
- 2024-09-12
- DOI
- https://doi.org/10.3390/ph17091201
- Citations
- 1
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39