CASE REPORT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY IN HIV

Progressive multifocal leukoencephalopathy (PML) is a neurological condition caused by the JC virus. PML is a demyelinating disease preferentially affecting the central nervous system. JC virus is a DNA virus of the polyomaviridae family. The virus remains latent in most immunocompetent hosts and rarely presents pathologically. In immunosuppressed hosts, however, a combination of poor cellular response of the host along with reactivation of the virus secondary to recombination of genes results in active disease. This case report described a 34 years old female patient with a HIV, PML.