EIF3B affects the invasion and metastasis of hepatocellular carcinoma cells via the TGFBI/MAPK/ERK pathway
Our results indicate that EIF3B functions as an oncogene in HCC that accelerates cell invasion, metastasis, and the EMT by stimulation of the TGFBI/MAPK/ERK signaling pathway. EIF3B is a potential target for the treatment of HCC.
Authors
- Yunbin Ye (ORCID: https://orcid.org/0000-0002-0256-987X)
- Ling Wang (ORCID: https://orcid.org/0009-0005-4954-4409)
- Wansong Lin (ORCID: https://orcid.org/0000-0002-4490-6133)
- Lingyu Zhang (ORCID: https://orcid.org/0000-0002-4297-903X)
- Zhifeng Zhou (ORCID: https://orcid.org/0000-0002-9178-9718)
- Jieyu Li (ORCID: https://orcid.org/0000-0002-9176-019X)
- Mingshui Chen
- Chuanzhong Huang
Institutions
- Fujian Medical University (CN)
- Fujian Provincial Cancer Hospital (CN)
Publication Details
- Journal
- Annals of Hepatology
- Published
- 2024-09-12
- DOI
- https://doi.org/10.1016/j.aohep.2024.101564
- Citations
- 6
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Science and Technology Projects of Fujian Province
- Fujian Medical University