FDG-PET and ASL MRI identify largely overlapping hypermetabolic and hyperperfusion changes in limbic autoimmune encephalitis
We identified suboptimal anatomical correspondence of abnormalities assessed with [<sup>18</sup>F]FDG-PET and ASL-MRI. Hyperperfusion and hypermetabolism might reflect differently AE-related pathophysiological correlates, but they both demonstrate ability to monitor disease activity. ASL-MRI is a promising marker of disease activity in AE and a favorable alternative to [<sup>18</sup>F]FDG-PET due to its cost-effectiveness, safety, and wide availability.
Authors
- Luca Roccatagliata (ORCID: https://orcid.org/0000-0001-8029-3947)
- Enrico Peira (ORCID: https://orcid.org/0000-0002-5834-8101)
- Luana Benedetti (ORCID: https://orcid.org/0000-0002-9540-9727)
- Antonio Uccelli (ORCID: https://orcid.org/0000-0002-2008-6038)
- Flavio Villani (ORCID: https://orcid.org/0000-0002-2762-4599)
- Lucio Castellan (ORCID: https://orcid.org/0000-0002-5463-8785)
- Martina Resaz (ORCID: https://orcid.org/0000-0002-5630-253X)
- Federico Massa (ORCID: https://orcid.org/0000-0001-5667-204X)
- Giacomo Rebella (ORCID: https://orcid.org/0000-0001-8625-1596)
- Silvia Daniela Morbelli (ORCID: https://orcid.org/0000-0002-7833-6095)
- Denise Cerne (ORCID: https://orcid.org/0009-0003-5411-1187)
Institutions
- Ospedale Policlinico San Martino (IT)
- University of Turin (IT)
- University of Genoa (IT)
Publication Details
- Journal
- The Quarterly Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2024-09-01
- DOI
- https://doi.org/10.23736/s1824-4785.24.03583-0
- Citations
- 3
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.11