Oncologic Outcomes of Incidental Versus Biopsy-diagnosed Grade Group 1 Prostate Cancer: A Multi-institutional Study
We compared the outcomes of patients with low-grade prostate cancer on active surveillance according to the type of their initial diagnosis. Patients who have low-grade cancer diagnosed on a procedure to relieve urinary symptoms (incidental prostate cancer) are followed less intensively and undergo curative-intended treatment less frequently. We also found that patients with incidental prostate cancer are more likely to have no cancer on their first follow-up biopsy than patients who have low-grade cancer initially diagnosed on a biopsy. These patients have a more favorable prognosis than their biopsy-detected counterparts and should be managed the same way as patients with negative biopsies if they undergo a subsequent biopsy that shows no cancer.
Authors
- Leonardo Quarta (ORCID: https://orcid.org/0009-0008-9523-3400)
- Fabrizio Moro (ORCID: https://orcid.org/0000-0001-8850-9239)
- M. Facco
- L. Da Pozzo (ORCID: https://orcid.org/0000-0002-7051-6980)
- Giorgio Gandaglia (ORCID: https://orcid.org/0000-0002-5052-721X)
- Andrew Julian Vickers (ORCID: https://orcid.org/0000-0003-1525-6503)
- Giovanni La Croce (ORCID: https://orcid.org/0000-0001-6209-8670)
- Joris G. Heetman (ORCID: https://orcid.org/0000-0002-9560-7387)
- Umberto Capitanio (ORCID: https://orcid.org/0000-0001-9225-1795)
- Emily Vertosick (ORCID: https://orcid.org/0000-0001-6948-9850)
- Andrea Salonia (ORCID: https://orcid.org/0000-0002-0595-7165)
- Peter Ka‐Fung Chiu (ORCID: https://orcid.org/0000-0002-1499-8372)
- Roderick C.N. van den Bergh
- Francesco Montorsi (ORCID: https://orcid.org/0000-0002-7267-4181)
- Isabel Heidegger (ORCID: https://orcid.org/0000-0003-1517-5746)
- Riccardo Leni (ORCID: https://orcid.org/0000-0003-0779-0984)
- Jonathan Olivier (ORCID: https://orcid.org/0000-0002-5409-2911)
- Timo Soeterik (ORCID: https://orcid.org/0000-0002-0259-8750)
- Fabio Zattoni (ORCID: https://orcid.org/0000-0002-4178-373X)
- Lorenzo Bianchi (ORCID: https://orcid.org/0000-0001-7321-1536)
- Sigrid Carlsson (ORCID: https://orcid.org/0000-0003-3553-5710)
- Xiaobo Wu (ORCID: https://orcid.org/0000-0002-4786-4637)
- Marco Roscigno (ORCID: https://orcid.org/0000-0002-5241-6767)
- Luca Lampariello
- Alberto Briganti
- Harm H E van Melick
- Giulia Giannini (ORCID: https://orcid.org/0009-0007-3241-3183)
Institutions
- Memorial Sloan Kettering Cancer Center (US)
- University of Padua (IT)
- Innsbruck Medical University (AT)
- Vita-Salute San Raffaele University (IT)
- Chinese University of Hong Kong (HK)
- Lund University (SE)
- Université de Lille (FR)
- Erasmus MC (NL)
- University Medical Center Utrecht (NL)
- St. Antonius Ziekenhuis (NL)
- Ospedale Papa Giovanni XXIII (IT)
- Azienda USL di Bologna (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
- University of Milano-Bicocca (IT)
- University of Gothenburg (SE)
Publication Details
- Journal
- European Urology Open Science
- Published
- 2024-08-20
- DOI
- https://doi.org/10.1016/j.euros.2024.08.004
- Citations
- 6
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.51
Funders
- Memorial Sloan-Kettering Cancer Center
- National Institutes of Health
- Sidney Kimmel Center for Prostate and Urologic Cancers
- National Cancer Institute