PATHOLOGY AND MEDICINAL PLANT TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE

Gastroesophageal reflux disease (GERD) is a prevalent chronic disorder characterized by the backflow of acidic gastric contents into the esophagus due to lower esophageal sphincter (LES) dysfunction. This condition causes esophageal mucosal damage, leading to symptoms such as heartburn and chest pain, and is associated with increased risks of severe complications, including esophageal adenocarcinoma.Aims:To review the current state of GERD management and assess the potential of photochemical plant-based treatments as alternatives to conventional therapies.Methods:A comprehensive literature review was performed to describe the status of GERD in detail while focusing on the emerging role of plant-based therapies in GERD management.Results:Traditional treatments for GERD are effective but often come with side effects and limitations. Plant-based treatments, particularly those with photochemical properties, are potential complementary therapies. Preliminary data suggest these alternatives may improve symptom management and patient outcomes.Conclusions:While standard treatments for GERD are widely used, their limitations necessitate exploring alternative options. Photochemical plant-based therapies offer a promising, supplementary approach, pending further validation through research and clinical trials.