Evaluations of Bone turnover in a sample of Iraqi Postmenopausal Hypertensive Obese Women

Background: Hypertension and osteoporosis are worldwide diseases with high prevalence; the study was done to estimate the correlation between hypertension and bone turnover in a sample of Iraqi postmenopausal women with hypertension and obesity. Materials and Methods: A cross-sectional study was done on 99 hypertensive obese postmenopausal Iraqi women (65 hypertensive obese and 34 normotensive non obese). The serum calcium (Ca), phosphorus (Pi), and alka line phosphatase (ALP) levels were measured as a represen tative of bone markers. Results: The results demonstrated that serum alkaline phosphatase is significantly elevated in the case group compared to the controls. No significant changes were observed in the levels of Ca and Pi in the patient group, while a significant increase in alkaline phos phatase was observed. Conclusions: The study shows that the changes in the bone markers in the patient group are important risk factors and contribute to osteoporosis, and it declares the effect of hy pertension on bone turnover markers in Iraqi postmenopausal women with hypertension and obesity.