Metformin impacts the differentiation of mouse bone marrow cells into macrophages affecting tumour immunity
Our study provides novel insights into the immunomodulatory properties of metformin in macrophages and its potential application in preventing tumour onset and in cancer immunotherapy.
Authors
- Aurélie Poli (ORCID: https://orcid.org/0000-0002-7986-0761)
- Petr V. Nazarov (ORCID: https://orcid.org/0000-0003-3443-0298)
- Alexandros Pailas (ORCID: https://orcid.org/0000-0003-4312-556X)
- Michel Mittelbronn (ORCID: https://orcid.org/0000-0002-2998-052X)
- Nathalie Legrave (ORCID: https://orcid.org/0000-0003-1172-4955)
- Frida Lind‐Holm Mogensen (ORCID: https://orcid.org/0000-0002-3497-2321)
- Alessandro Michelucci (ORCID: https://orcid.org/0000-0003-1230-061X)
- Katrin Neumann (ORCID: https://orcid.org/0000-0002-3858-3171)
- Nathalie Nicot
- Eric Van Dyck (ORCID: https://orcid.org/0000-0001-8614-2402)
- François Bernardin (ORCID: https://orcid.org/0000-0002-6329-5542)
- Andrea Scafidi (ORCID: https://orcid.org/0000-0002-3089-2439)
- Anne Grünewald (ORCID: https://orcid.org/0000-0002-4179-2994)
- Paul Antony (ORCID: https://orcid.org/0000-0002-0450-9301)
- Sandro L. Pereira
- Eleonora Campus (ORCID: https://orcid.org/0009-0008-2911-5887)
Institutions
- University of Luxembourg (LU)
- Luxembourg Institute of Health (LU)
- Laboratoire National de Santé (LU)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e37792
- Citations
- 7
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.64
Funders
- Fonds National de la Recherche Luxembourg