COMPARATIVE ANALYSIS OF RENAL PARAMETERS TEST RESULTS: FULLY AUTOMATED VS SEMI AUTOMATED BIOCHEMICAL ANALYZER

Background: Clinical Biochemistry tests comprise over one third of all hospital laboratory investigations in India. Thus it's important to ensure overall quality management of the laboratory in terms of accuracy, reliability and timeline of reported test results. The present study aims to evaluate the test performance and the reliability of the results obtained by semi-auto analyzer as in comparison to fully-auto analyzer. Total 70 patients we Methods: re enrolled in this study who were advised for renal function test investigation in S.N. Medical College, Agra. The blood samples were analyzed for three biochemical parameters- Creatinine, Urea and Uric Acid on both ERBA Chem 7 (semi-auto analyzer) and Selectra Pro M (fully-auto analyzer). Statistical analysis was carried out using independent student t test, Pearson correlation, Bias percentage and Bland-Altman analysis using Microsoft Excel 2016 and Python programming language. The p-value <0.05 was considered to be statistically signicant. In our study, we found a non-signicant difference in t Results: he mean value of all the three parameters- urea, creatinine and uric acid between the readings obtained on fully and semi auto analyzers while the correlative study showed signicant positive correlation for all the parameters. Bias percentage were all in acceptable range except the urea and the Bland-Altman analyses showed that the readings from both semi and fully auto analyzers were in agreement with each other. The ndings of this study suggest that the semi-auto analyzer can be used Conclusion: as a reliable alternative of fully-auto analyzer.