Transarterial Chemoembolization for Inoperable Early-Stage Hepatocellular Carcinoma in Patients with Child-Pugh Grade A

Background: Gastrointestinal cancer As the main killer of cirrhotic patients, HCC is a major worldwide health problem, accounting for more than 5% of all malignancies. The selection of the most appropriate treatment option for (HCC) patients depends not only on tumor burden but also on liver function and the general performance status of patients. It has recently been demonstrated that (TACE) provides a survival benefit and become a standard treatment in selected patientsThe goal of this review was to talk about how TACE responds to tumours in people who have HCC that is Child Pugh Grade A. Results: Patients with Child-Pugh Grade A early-stage hepatocellular carcinoma who are unable to undergo surgery may benefit greatly from TACE, as shown by the study's 60% complete response rate. Importantly, the research found that a good prognosis after TACE is strongly predicted by a lower tumour size, the lack of an expanded belly, and ultrasonography homogeneity. In order to optimise patient selection and improve clinical results for HCC patients, it is crucial to consider tumour features and clinical presentation when predicting TACE outcomes.

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Publication Details

Journal
Benha Journal of Applied Sciences
Published
2024-08-31
DOI
https://doi.org/10.21608/bjas.2024.315683.1480
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

Transarterial Chemoembolization for Inoperable Early-Stage Hepatocellular Carcinoma in Patients with Child-Pugh Grade A

Mohamed Abdel Hameed Ahmed Elserwi, Mohamed Mohamed Hosney Faheem, Talal Ahmed Youssef Amer
Benha Journal of Applied Sciences
Hepatocellular Carcinoma Treatment and Prognosis
article

Transarterial Chemoembolization for Inoperable Early-Stage Hepatocellular Carcinoma in Patients with Child-Pugh Grade A

Mohamed Abdel Hameed Ahmed Elserwi, Mohamed Mohamed Hosney Faheem, Talal Ahmed Youssef Amer
article en

Abstract

Background: Gastrointestinal cancer As the main killer of cirrhotic patients, HCC is a major worldwide health problem, accounting for more than 5% of all malignancies. The selection of the most appropriate treatment option for (HCC) patients depends not only on tumor burden but also on liver function and the general performance status of patients. It has recently been demonstrated that (TACE) provides a survival benefit and become a standard treatment in selected patientsThe goal of this review was to talk about how TACE responds to tumours in people who have HCC that is Child Pugh Grade A. Results: Patients with Child-Pugh Grade A early-stage hepatocellular carcinoma who are unable to undergo surgery may benefit greatly from TACE, as shown by the study's 60% complete response rate. Importantly, the research found that a good prognosis after TACE is strongly predicted by a lower tumour size, the lack of an expanded belly, and ultrasonography homogeneity. In order to optimise patient selection and improve clinical results for HCC patients, it is crucial to consider tumour features and clinical presentation when predicting TACE outcomes.

Benha Journal of Applied SciencesVol. 9(8)
Mansoura University (EG), Benha University (EG)
Zero hunger
Openalex Percentile: Top 75%
Hepatocellular Carcinoma Treatment and Prognosis
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