Comprehensive Analyses of Somatic Copy Number Alterations and Mutations Based on the Adenoma–Carcinoma Sequence

We suggest that considerable SCNAs and TP53 mutations are required for progression from adenoma to carcinoma within the same intramucosal neoplastic lesion.

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Publication Details

Journal
Genes Chromosomes and Cancer
Published
2024-09-01
DOI
https://doi.org/10.1002/gcc.23267
Primary Topic
Genetic factors in colorectal cancer
Type
article
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article

Comprehensive Analyses of Somatic Copy Number Alterations and Mutations Based on the Adenoma–Carcinoma Sequence

Wataru Habano, Naoki Yanagawa, Noriyuki Uesugi, Hiromu Suzuki et al.
Genes Chromosomes and Cancer
Genetic factors in colorectal cancer
article

Comprehensive Analyses of Somatic Copy Number Alterations and Mutations Based on the Adenoma–Carcinoma Sequence

Wataru Habano, Naoki Yanagawa, Noriyuki Uesugi, Hiromu Suzuki, Tamotsu Sugai, Mitsumasa Osakabe
article en

Abstract

We suggest that considerable SCNAs and TP53 mutations are required for progression from adenoma to carcinoma within the same intramucosal neoplastic lesion.

Genes Chromosomes and CancerVol. 63(9)
Sapporo Medical University (JP), Iwate Medical University (JP), Southern Tohoku General Hospital (JP)
Good health and well-being
Openalex Percentile: Top 76%
Genetic factors in colorectal cancer
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